Functional Medicine – Lab Testing

Functional Medicine – Lab Testing


At Spade a variety of advanced laboratory testing will be performed to identify the root cause of your conditions. We work with a variety of laboratory companies to assist with these testing. We have negotiated a discounted rate for our patients to ensure they are affordable.

Commonly ordered tests are:

AMINO ACIDS TESTING This test uncovers problems in amino acid intake and absorption by measuring levels of essential and nonessential amino acids. Imbalance or insufficient amino acids can affect a wide range of body functions, producing symptoms that negatively affect the quality of life. Amino acid testing helps the practitioner gain insight into dietary protein intake and digestion/absorption.

FATTY ACID PROFILE Fatty acid imbalances can be a causative factor in a variety of chronic health conditions, including chronic pain/inflammatory conditions, depression, cardiovascular, aging and neurological diseases. This blood test measures levels of polyunsaturated fatty acids, trans fats, saturated fats, and fatty-acid ratios. Dietary and nutraceutical intervention can be used to correct imbalances.

NUTRIENT AND TOXIC ELEMENTS This test is uses whole blood as an indicator of body pools of essential elements as well as toxic elements aluminum, arsenic, cadmium, lead, and mercury. Whole blood generally reflects increased or recent exposure to toxic elements. Nutrient elements are measured in red blood cells and toxic elements are measured in whole blood.

HORMONE TESTING Hormone testing includes an Adrenocortex Stress Profile which evaluates the key stress hormones, cortisol and DHEA. Samples are collected throughout the day to allow for circadian rhythm assessment. Adrenal hormone testing may uncover biochemical imbalance, which can adversely affect Mood, Sleep, Immune defense, Thyroid function, Levels and function of gonadal hormones (progesterone, testosterone, and estrogens), Weight control, Resistance to stress, Energy, Cognitive function and Cardiovascular health

INTESTINAL ANTIGENIC PERMEABILITY SCREEN(Leaky Gut Syndrome)Blood antibody testing for proteins associated with increased gut permeability.

BLOOD-BRAIN BARRIER PERMEABILITY SCREEN Increases in blood-brain barrier proteins are associated with a wide variety of neuro-inflammatory conditions.

PLASMA METHYLATION PROFILE Normal metabolism of the amino acid methionine is critical for cellular methylation of DNA, proteins, and neurotransmitters. Aberrant methionine metabolism can occur in anyone at any age and can be associated with numerous health consequences, including cardiovascular and neurological diseases, and cancer. The Methylation Profile provides a functional assessment of the phenotypic expression of common SNPs by evaluating levels of methionine, cysteine, SAM, SAH, homocysteine and cystathionine, and provides the important “methylation index,” a ratio of SAM to SAH. This test is useful for Autism, schizophrenia, bipolar disorder, Birth Defects, Cancer, Cardiovascular Disease, Congenital Heart Disease, Detoxification Impairment, Down Syndrome, General Health and Longevity, Genetic Disorders, Immune Dysfunction, Neurodegenerative Diseases, Nutritional Deficiencies and Psychiatric Disorders.

FOOD SENSITIVITY / FOOD ALLERGY TEST Blood measurement of IgG (immunoglobulin G) directed against specific food proteins is a useful guide for structuring elimination diets in many chronic conditions. Individuals with neurological, gastrointestinal, and movement disorders often suffer from IgG food allergies. These individuals may continue to eat offending foods unaware of their potential effects. Symptoms related to IgG food sensitivity may appear anywhere from hours to days after eating making identification of the offending foods difficult without testing. Elimination of IgG positive foods can improve symptoms of irritable bowel syndrome, autism, AD(H)D, cystic fibrosis, rheumatoid arthritis, and epilepsy, among others.

APOE GENOTYPE TESTING It allows for identification of those at increased risk for Late Onset Alzheimer’s disease, specifically carriers of one or two copies of ApoE4. This “ancestral” gene is found in 30% of the population. The frequency of Alzheimer’s disease and mean age at clinical onset are 91% and 68 years of age in carriers of two copies of this gene, 47% and 76 years of age in carries of one copy of this gene.

MOLD ILLNESS The panel of bloodwork used for the diagnosis and management of mold illness (Chronic Inflammatory Response Syndrome, CIRS)

23 AND ME DNA TESTING It is to identify the common genetic variations known as Single Nucleotide Polymorphisms (SNPs) that are clinically relevant and nutritionally actionable.